Digifab

I was asked to dose Digifab (for digoxin toxicity) today and I have never done a Digifab order before. There are 2 digoxin antidotes - Digibind and Digifab. We carry Digifab. It comes 40 mg/vial. There is a chart in the package insert for dosing. You either have to know the body load of digoxin in mg and divide by 0.5 OR or you have to know the digoxin level. In this case, we had a level (thank goodness....b/c what does body load mean?). You also need to know their weight. The chart will tell you how many vials to give.

1 vial of Digifab and Digibind will bind to 0.5 mg digoxin.

Symptoms of life threatening toxicity due to digoxin overdose include severe arrhytmias, bradycardia, heart block not responsive to atropine, and/or hyperkalemia.

Thank you for your interest in reading about Digifab.